Radium Bromatum

Proving of Radium Bromide

By GUY BECKLEY STEARNS, M. D., NEW YORK CITY

The Homeopathician, Vol. 1, N°1, January, 1912

One milligram of the 1,8oo,ooo ac­tivity of pure RADIUM BROMIDE was weighed out, and the trituration was begun with that quantity. The prov­ings were made from the 6x, 12x, and the 3ox triturations.

A measurable quantity of this ac­tive and powerful salt was present in each of these strengths, as was shown by the electroscope and the photo­graphic plate. During the action of the 6x, the urine of the provers was rendered radio-active. All the ex­perimenters developed symptoms, some of which persisted several weeks after discontinuing the drug. All of them experienced sensations which are characteristic both as to nature and location.

The pains were located deep in the joints, and were described as being in the articulations. They were of two kinds:

Dull ache, which appeared gradu­ally and stayed with the prov­er a long time.

Sharp pains, which appeared and disappeared suddenly, or ap­peared suddenly and gradually wore away.

These pains changed place, and in some provers alternated from side to side. In two, the right side was more affected than the left.

Invariably occurred within twenty-four hours.

These pains are particularly significant when considered in conjunction with their frequent occurrence in the large-toe joints, and confirm the very evident curative value of RADIUM in gout and chronic rheumatoid conditions.

Nearly all had pains in one or the other large-toe joints.

All had pains at the sacro-lumbar junction, deep in the articu­lation ; aching was dull and intense.

Its selective action in the lumbo-sacral region should prove useful in acute condi­tions when lumbago is a symptom.

All the men provers were very rest­less with the pains, compelled to move about.

Motion aggravated the pains at first, but continued motion relieved them.

They had strong desire for the open air, and all the symptoms dis­appeared or were better when going out-of-doors.

(These two modalities were absent in the women provers.)

In most cases there was marked aggravation of all the symp­toms from the latter part of the afternoon until after dinner.

General symptoms were better af­ter eating,-in most provers.

PHYSICAL GENERALS.

A strong desire to stretch the mus­cles, with relief from the stretching, was present.

Intense weakness of the lower limbs, with languor, developed in all.

Numbness, when crossing the legs, occurred in some.

Soreness of the muscles all over the body developed in two.

The foregoing symptoms and modalities were the first to appear in the proving, and were present in all cases.

The tired, weak sensation in the lower ex­tremities, as the provers said, « from the small of the back, down, » was so characteristic as to be considered a key-note of the remedy. This was so pronounced as to make a strong effort necessary in walking, though continued walking gave relief.

Mental symptoms were present in some of the provers, but usu­ally developed some time after the physical.

Irritability and easy vexation first appeared,

Depression, discouragement and dissatisfaction then appeared.

In one of the women provers the depression reached a very distressing point, so that she would waken at night in fear, and desire light and company. Her sleep was restless, and she was troubled by dreams, which awakened her, and for some time she could not be sure whether they were real or not. Dreams were always troubled ; of fire ; of attempting suicide ; of physical exertion. Unlike most of the provers, she was not especially better in the open air, but obtained much relief from a bath.

Apprehension, as though something would happen, with fear in the dark.

Concentration difficult.

Vertigo was a prominent symptom in two provers.

After three weeks, in one, brought on by rising or reading stead­ily.

Intense, with tendency to fall to the left, necessitating walking with the left hand against the wall, for support, continuing for a day or two, appearing alter he had awakened sud­denly with à, sensation- of an electric shock through the body, in the second prover.

Relief in the open air.

Relief after eating and from ly­ing.

Worse when sitting or walking.

These modalities were strongly expressed in this condition.

The physical cause of this vertigo was not apparent from any of the examinations made, though the symptom was distinctly an effect of the drug.

Terrific headache over the left eye, extending to the occiput. Relieved by warmth. Aggravated by cold and pressure.

Aside from the headaches, however, cold was more agreeable than warmth.

Dull, frontal headache, with a tight sensation.

Headache from the occiput up over the vertex.

Extremely dull, frontal headache, in one prover, three weeks after discontinuing the drug.

Aggravation in late afternoon, marked, in most of the head­aches.

Relief in open air, also marked in most headaches.

This last amounted, in many ex­perimenters, to an air-hunger.

Pains simulated the neuralgic and rheu­matic types, never the gastric; and, in this respect, correspond to the general character of the action of the drug, as already suggested.

Heaviness of the eye-lids was caused by the drug.

Distinct ptosis, in one case, worse in right eye, with lachrymation.

Discharge, thin, yellowish, puru­lent, stuck the lids together and formed a yellow crust, oc­curred after three weeks, in the ptosis subject.

Irritation of the margins of the lids, in another.

RESPIRATORY ORGANS.

The respiratory organs were affect­ed by rather violent symptoms.

Rawness or soreness in the throat was the beginning.

Worse, swallowing.

Relieved by cold drinks.

Dry, teasing cough, after a day.

Occasioned by tickling sensation in the larynx.

Kept prover awake at night.

Worse lying down, and soon after going to bed.

After beginning to cough, the sub­ject could not stop.

Tickling in the throat was very disagreeable and persistent, re­lieved by open air.

During the cough, there was dis­tinct aversion to sweets.

Bruised, sore sensation in chest in two provers who did not de­velop the cough.

In the region of the sternum.

As though the two sides of the chest were pushed together.

Soreness of the throat, with splint­ery sensation, preceded sore sensation in the chest in one of the provers.

Relieved by swallowing cold water.

Expectoration occurred in only one case, where the irritation be­gan with soreness of the throat, followed by a hacking cough.

Frothy, white mucus, which soon became tenacious.

Constriction sensation was felt principally about the heart, in­tense.

Cough was so troublesome in one prover that it kept her awake several nights, and had to be palliated.

Spongia, Ignatia and Coccus cacti were given with little relief but Rhus venenata stopped the cough at once.

Rhus venenata, in fact appears to be the best antidote for RADIUM, which is another significant point in relation to its gouty symptoms.

Although the cough symptoms were very severe, they did not appear to be due to any inflammatory condition of the longs, but to a laryngeal irritation.

DIGESTIVE ORGANS were somewhat affected.

Aversion to sweets developed.

Empty, all-gone sensation.

Craving for fresh pork, during and after the proving, in one man.

Much gas formed in the intestines and there was

Some griping, most characteristic modalities being

Relief from walking about, and

Relief from passing flatus.

Sluggishness of the bowels was de­cided, with

Retarded, though soft stools, or

Alternate diarrhœa and constipa­tion, with offensive flatus.

Stool was clayey in consistency, in one case sticky.

Rectum sore and excoriated during the movement, in cases of diarrhœa.

The total effect on the digestive organs can be characterized as sluggishness and ap­pears to be incidental to the general depress­ing effect of the drug, rather than to any spe­cific or selective relationship to those organs.

URINARY ORGANS.

Some atony of the urinary organs was caused, resulting in slow­ness in starting the urine.

Urates were increased in quantity.

Albumin was found in the urine in most of the provers.

A few granular casts were observed in one case.

The irritative action of RADIUM on the kidneys may be due to its direct irritating qualities during its excretion, for there was enough RADIUM in the 6x to make the urine radio-active and there was enough in the 30x to affect the photographic plate. On the other hand, RADIUM may have a selective action on the kidneys.

METABOLISM of the body was pro­foundly influenced, as was shown by

Increase in the specific gravity of the urine, and

Increase in the elimination of the uric acid derivatives.

Loss of several pounds occurred in one of the male provers, dur­ing the experiment

SEXUAL ORGANS.

Sexual functions were at first stimu­lated in the male, causing

Frequent nocturnal emissions, and

Amorous dreams.

Diminution of the sexual desire ap­peared later.

Menstrual flow was more profuse in the women,

Flow protracted.

Less painful than usual.

Headache usually present during menstruation was absent.

The women claim to have been much benefited by the proving, in regard to their menstruation and in their general health.

There were some strong SKIN symp­toms.

Small, red papules on the face and chest, developed in some.

Similar eruption between the shoul­ders, in one.

Itching, worse in early evening and when undressing; better in bed and relieved by scratching.

Sensitive papulæ over entire body, in another.

Scaly, itching eruption on the an­terior surface of the thighs and the forearms was caused in another.

Itching better from warmth and scratching; worse from bathing.

Itching developed and partly dis­appeared in a scaly eruption on the back of the hands, one of the provers had developed after working for several years with X-ray and with RA­DIUM emanations. This always troubled him by cracking and bleeding in cold weather.

A sebaceous cyst developed over the lower part of the sacrum of one other prover.

Intense sensitiveness of the corns was observed in two provers.

Old bunions which had not been troublesome in a long time, be­came inflamed and painful, in the same provers.

This last symptom is quite striking and shows the relation of the drug to the large toe joint and to irritated epithelial structure. Dr. J. T. Kent gave the 2ooth to an old gen­tleman on two different occasions, and several weeks after each administration a painful eruption came out on the body, without sub­jective symptoms. This exfoliated as bran­like scales, so that the sheets of his bed were covered in the morning.

CIRCULATORY SYSTEM.

The effect on the circulatory sys­tem was of lowered tone as was evidenced by lowered blood pressure.

The elements of the blood itself were altered resulting in

An increase of the leucocytes to as much as 30 to 50 per cent above normal. This was con­fined to the polymorphonuc­lear neutrophyles, showing an increase in the protecting cells of the body.

The small lymphocytes were de­creased.

In the foregoing, I have endeavored to select the most characteristic symp­toms and modalities as they were pre­sented by the provers. A detailed re­cital of the symptoms would be both tedious and confusing. However, a thorough understanding of the drug can be obtained only by studying the complete record which has appeared in the journal of the American Insti­tute of Homœopathy and in the North American journal of Homœopathy.

The experiment was conducted with seven provers, four men and three women, and was due to the scientific spirit and initiative of Dr. Dieffenbach. Every prover was care­fully examined before and during the proving, and observations were made on the urine and the blood. Dr. Cope­land, Dr. Crump, and Dr. Sayer as­sisted Dr. Dieffenbach in this task. My work was the lesser one of ques­tioning the subjects and bringing out the modalities.

As far as it has gone, this proving has been conducted as carefully, and as scientifically as modern clinical methods will allow, and is in every way up-to-date. But it can only be considered a foundation, for with the limited number of provers, there have been only hints of many of the possibilities of the drug. Clinical re­ports are needed also, to confirm and fix the value of the modalities, some of which appear to be somewhat con­tradictory. These contradictions per­tain to the aggravations and ameliora­tions from warmth and motion, and probably have to do with their re­lation to local and general conditions; e. g., some local conditions were bet­ter from warmth, while the general symptoms were better from cold.

The work has demonstrated, in a way nothing else could accomplish, how wrong is the idea of those who clamor for a boiled-down materia medica. On the contrary, a record of every symptom is necessary for a true comprehension of the complete action of any drug. General characteristics are but the composite expression of the complete record of such symp­toms as are grouped about some sin­gle function or part of the body, or of all taken together, and no symptom can be omitted.

In this proving, the character of the symptoms; the appearance of cer­tain symptoms, weeks alter the ad­ministration of the drug; and the per­sistence of other symptoms, show RADIUM to be a drug of very deep ac­tion, and bear out the experiences of its use in more material doses.

Its well-marked modalities should make it a remedy easy of verification.

Review of Dieffenbach’s Proving

The literature of Homœopathy has recently been enriched by the record of the proving of RADIUM BROMIDE conducted by Dr. William H. Dief­fenbach in collaboration with Drs. Royal S. Copeland, Walter Gray Crump, Henry C. Sayre and Guy B. Stearns.

The purest obtainable RADIUM BROMIDE was triturated by Mr. E. W. Runyon, of New York, to the 6x, 12x and 30X potencies. « The provers noted their daily symptoms for one week. » In addition to this, some symptoms were developed in the person who made the tritura­tion. The report was presented in the programs of the American Insti­tute of Homœopathy at Narragan­sett Pier, and the International Con­gress of Homœopathy at London, during the past summer, an outline of the same having been. contributed to the Society of Homœopathicians, meeting in Chicago. It has been printed in the journal of the A. I. H. and in the North American journal of Homœopathy. The following ré­sumé is based on that report.

RADIUM is a long acting, deeply acting remedy, its pace being similar to that of Sulphur and Silica. Some of the provers observed symptoms appearing or recurring from one to four or more weeks alter the admin­istration of the remedy in the 6x and I2x potencies. This fact is intensely significant, a warning to guide those who prescribe it. When the power of potentized substances is once comprehended, it is clear that in this form it is possible to engraft on the system a powerful drug miasm, creating a sensitivity to its action in those who do not at first present a symptom image of the remedy. Such forced sensitivity and insidious ef­fects are not easily eradicated. When it is homœopathically indicated, if administered in too frequent doses, the first good will be destroyed and followed by disaster through the interfering action of the later doses. The insidious poisonous effects in such cases, progressing in those sensitive to it at the beginning of its adminis­tration, may continue throughout the life time and be transmitted as a drug miasm. The substance acts so deeply in the organism, entering the realm of the very construction of tissues.

Those who have worked with it have been impressed with the resem­blance of its action to rheumatism, (especially of gouty form), malignant and skin affections, nephritis, pul­monary inflammation and intestinal disturbances.

The remedy has an evident affinity for joints, muscles, skin, kidney and mucous membrane of the respiratory tract, but for the most satisfactory results these tissue effects must not be the chief guide for the prescriber unless he courts disap­pointment at the outset. Not all forms of such affections, not all patients suf­fering arthritis, albuminuria, obstinate skin eruptions of eczematous type and malignant disorders are to be assumed proper subjects for this powerful weapon. If it be held as an instrument in our armamentarium to be tried indiscriminately, if possibly it may suit the case, not only disappointment but woeful abuse must follow its employment.

The certain guide to determine what cases should receive this mar­velous agent and may be benefited by it, is similar to the guide for all our remedies, namely the symptom­image as revealed in the « symptoms of the patient, » those that character­ize the man in disorder. .

The Radium subject suffers IN­TENSE MENTAL DEPRESSION, for which nothing in the environment or life circumstances appears accountable. (In the prover, depression usually present during menstrual period was absent during the proving.) Sensa­tion as if something terrible would happen may accompany this. She is afraid to be alone, especially in the dark. Painfully IRRITABLE, he is vexed, out of all proportion to the trifling occurrences that call forth his displeasure. Anxiety; RESTLESSNESS AT NIGHT IN BED, when awake with pain or during sleep. Dullness, think­ing is difficult. Confused after waking.

WEARINESS; aching through the entire body or of affected parts. INCLINA­TION TO RECLINE. Loss of springiness in walking.

VERTIGO, with tendency to fall; gradually disappears; AMELIORATED IN OPEN AIR.

CRAVES OPEN AIR; AIR HUNGER; AMELIORATED IN OPEN AIR. Ameli­oration FROM CONTINUED MOTION; from motion in bed, after eating; after sleep; during menses; from warmth applied; from warm clothing and from bath. COMPLAINTS, INTERMIT­TENT, PERIODIC. Disappearing grad­ually (pains and other complaints). Aggravation AFTERNOON; EVENING; night; before menses.

Pains BURNING; INTERMITTENT; soreness, stiffness, STICKING. SENSA­SATION OF DRYNESS IN -MUCOUS MEM­BRANES. Sensation of warmth or heat, internally. Heat in bed, with desire to uncover. Chilliness inter­nally. Perspiration absent or scanty. Succession of chill then heat, per­spiration absent. Tickling sensation in mucous membranes.

Blood pressure DECREASED. Blood vessels contracted; Blood altered by increased number of leucocytes; IN­CREASED NUMBER OF POLYMORPHONU­CLEAR NEUTROPHILES (the protecting tells), DECREASE IN SMALL LYMPHO­CYTES.

Drowsiness during the day. Sleep disturbed by restlessness and dreams. Dreams vivid; exciting; active; of fire; of suicide.                                                                  J. C. L.

Eighty per cent of our business men are addicted to « nervous rush, » but it does not spell efficiency. On the contrary, it means waste of energy, loss of time, more mistakes, a dull brain, and a  » tired out » state of existence. The remedy is poise.

                                                  C. D. LARSON, in January « Efficiency. »